Although the exact causes of cluster headaches are not fully understood, the trigeminal nerve may play a significant role in most cluster headache attacks. When this nerve overreacts to stimuli and misfires, it leads to pain and other symptoms such as nasal congestion, tearing, and conjunctival redness.
While the symptoms of cluster headaches overlap with other types of headaches, this condition has unique features that aid in diagnosis. Let’s look at these features:
Although each headache is relatively brief, the pain can be intense, disruptive to sleep, and life-limiting. Most people affected by cluster headaches will experience cluster periods (bouts of frequent attacks) lasting for months before a remission period.
Cluster headaches can be chronic or episodic, depending on the frequency of the attacks and the length of the remission periods. Let’s look at these types of cluster headaches below.
A cluster period can last between 2 weeks and 3 months. During this time, you may experience headaches every other day or up to eight times a day. You have episodic cluster headaches if you have pain-free periods lasting at least three months. Many people with episodic cluster headaches have seasonal patterns, with clusters triggered by temperature changes in spring or autumn.
If you don’t experience any breaks between clusters, or if the periods of remission are shorter than three months, your condition is categorized as “chronic.” Chronic cluster headaches affect 2 out of 10 people with cluster headaches and can be severely debilitating.
Cluster headaches are rarer but more severe than migraines. Many patients experience multiple types of head pain. Cluster headaches reach full intensity within minutes, leading to excruciating pain that often affects one side of the head.
Cluster headaches can affect your life for weeks or months at a time and tend to recur at the same time each day. Nighttime headaches are often more severe than those experienced during the day, leading to sleep disturbances and sleep deprivation.
This pain and lack of sleep can prevent you from being productive at work and lead to inhibited concentration and restlessness.
Below, we’ll look at the telltale signs that you may have cluster headaches.
Tip: If your symptoms last for 2 days or more, and you experience abnormal symptoms like shortness of breath, nosebleeds, vision loss, or high fever, seek emergency medical care immediately.
Because cluster headaches involve the trigeminal nerve, the pain is localized to one side of the face. The pain may shift from one side to the other in different attacks but rarely within the same attack.
You may also experience piercing and stabbing sensations accompanied by throbbing pain and pulsating veins, usually behind or around one eye. The pain reaches maximum intensity in as little as 5-10 minutes and can last up to 3 hours before decreasing suddenly.
Unlike migraines, which often lead you to rest in a dark and silent room, cluster headaches may make you restless and agitated. It’s not uncommon for people with cluster headaches to rock back and forth while holding their head during an attack.
People with cluster headaches may also experience temporary nasal congestion.
Although the relation between the two conditions isn’t clear, a 2013 study provides two possible explanations:
Excessive sweating and flushing, usually localized to the forehead and cheeks, are common symptoms of cluster headaches. Studies from 1987 and 1988 concluded that this symptom is caused by the trigeminal nerve’s reduced ability to control autonomic functions, such as sweating and temperature control.
Droopy eyelids and pupil constriction are symptoms of a common comorbidity of cluster headaches – Horner’s syndrome.
This condition is present in 10% of those with cluster headaches and usually lasts only during the main headache attack. However, in severe cases of prolonged or chronic cluster headaches, damage to the pathways that connect the facial muscles to the brain may cause permanent Horner’s syndrome-like symptoms.
Cluster headaches share similarities with other headache syndromes, such as migraines. Common migraine-like accompanying symptoms in people with cluster headaches include nausea and vomiting.
These symptoms, especially when accompanied by seizures, changes in vision and alertness, and drowsiness, may indicate that your condition requires immediate medical care.
Chronic headaches can cause sensitivity to light and sound, especially during an attack. This symptom is due to temporary changes in how the brain processes visual and auditory stimuli, making sounds and lights more painful than usual.
In most cases, cluster attacks and single headaches strike suddenly and without warning. However, according to a 2018 study, around 7% of patients experience warning visual and auditory signs known as “aura.”
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Cluster headaches are considered primary headaches, meaning the pain is the condition itself, with no underlying issues causing it. This contrasts with secondary headaches, which can be caused by health conditions and events such as tumors, arterial tears, blood clots, and sinusitis.
This characteristic of cluster headaches, coupled with their rarity, makes studying their causes and risk factors challenging. Consequently, the exact cause of cluster headaches often remains unclear.
However, you are likely to experience a cluster headache when an external stimulus triggers one or more nerve pathways linked to the hypothalamus in the brain. The hypothalamus manages several bodily functions, including the sleep cycle, blood pressure, heart rate, body temperature, and sensations such as thirst.
Below, we’ll explore some common triggers of cluster headaches. It’s important to note that these triggers are not the root cause but rather stimuli that may provoke an attack in patients already suffering from cluster headaches.
Understanding what triggers a new round of headaches can help you postpone or prevent an attack while extending the period of remission.
Males are 2.5 times more likely than females to suffer from cluster headaches. This condition can emerge at any age but is often diagnosed in adults aged 30 to 40. Additionally, individuals with a family member diagnosed with cluster headaches are 5-18 times more at risk of developing this condition.
During a cluster period, even a single alcoholic drink can trigger an attack.
Substance use can be a significant factor in initiating a cluster of headaches and can also increase your risk of developing this condition over your lifetime. Smokers are more likely to have cluster headaches.
Some substances that are risk factors for cluster headaches include:
Certain lifestyle factors may act as triggers for cluster headaches. These factors often create physical or psychological stress, impacting the hypothalamus, the trigeminal nerve, and the nervous system as a whole. High levels of stress increase the likelihood of dysfunctions.
These factors include:
Environmental changes are among the greatest risk factors for cluster headache attacks. Many patients’ attacks are related to changes in seasons. Allergies and conditions such as sinusitis, coupled with rapid temperature changes, can trigger cluster headaches. Some people with this condition may mistake cluster headaches for allergies or stress.
Other environmental factors that might cause an attack during a cluster period include:
High levels of stress, as well as emotional and psychological conditions such as anxiety, are recognized risk factors for migraines and other types of headaches. Studies conducted in 2006 have linked extreme emotional stress to cluster headache attacks as well.
Due to the rarity of cluster headaches, they are often misdiagnosed as other types of headache syndromes, as well as sinusitis and seasonal allergies.
Additionally, there is no specific test designed to diagnose cluster headaches. A specialist will usually combine a range of exams and tests to determine the type of headache syndrome you have or whether the pain is due to an underlying health condition.
Some of these assessments include:
Patients with cluster headaches often receive a diagnosis from a neurologist or other headache specialist.
As mentioned, the symptoms of cluster headaches overlap with those of other conditions. This, combined with the fact that over 200 types of headaches have been identified, makes it challenging for patients to receive a timely and accurate diagnosis.
Generally, cluster headaches are primary headaches, meaning they are not caused by an underlying illness, and the pain itself is the condition. However, cluster headaches are often misdiagnosed as other secondary health conditions that could cause head pain, such as:
According to a study conducted in 2000, people with cluster headaches experience a delay of nearly 7 years before obtaining a diagnosis and often consult an average of 4.3 physicians before being correctly diagnosed.
Being misdiagnosed isn’t inconsequential. Over 70% of those with cluster headaches undergo unnecessary magnetic resonance and other scans, while 4% face unnecessary surgical procedures to correct their sinus or a deviated septum.
Ultimately, obtaining the correct diagnosis is the first step to finding an appropriate treatment for cluster headaches. Let’s look at the treatment options available in more detail below.
Although cluster headaches are considered rare, they can be excruciating and life-limiting for those who suffer from them. To understand the extent of their impact, it’s important to note that this type of headache is sometimes referred to as a “suicide headache” due to the increased suicidality of patients experiencing or anticipating a cluster headache.
While there is no permanent cure for cluster headaches, your physician is likely to recommend two lines of treatment:
Let’s look at the most common treatments recommended by physicians for cluster headaches.
Several medications are prescribed to ease the intensity of a cluster attack and prevent further attacks. These are delivered as nasal sprays, injections, or capsules and include:
Preventive medications that may stop attacks before they happen include corticosteroids like prednisone, lithium carbonate, verapamil, and divalproex sodium.
One of the most efficient treatments for attacks already underway is inhaling pure oxygen. This treatment is administered by a healthcare professional through a face mask, usually in 15-minute intervals.
Additionally, a 2000 study found that many patients with cluster headaches are often misdiagnosed and prescribed medications like antibiotics and propranolol, which are not specifically intended for treating this condition.
Exercise can benefit people with cluster headaches both directly and indirectly.
Daily physical activity can boost sleep quality, reduce stress, and trigger the release of the body’s natural painkillers, endorphins. Additionally, maintaining an active lifestyle and reducing the consumption of alcohol and nicotine may improve blood circulation and help manage headache disorders.
If you suffer from cluster headaches, moderate exercise can help prevent and alleviate attacks. Mind-body disciplines like yoga and breathing exercises are particularly beneficial. Let’s look at the benefits of these activities below:
Complementary therapies such as massage and physical therapy can relieve pain from cluster headaches. Massages can trigger the release of pain-killing, feel-good hormones such as endorphins. Additionally, massages and physical therapy can improve conditioning, boost blood and oxygen circulation, reduce muscle tension, and lower stress levels.
Some self-massage techniques that may help include pressing with the thumbs just above the bridge of the nose, performing circular movements on the temples, and lightly pinching your eyebrows, all while taking deep breaths.
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